Being in a band can be as grating as it is gratifying.

From lackluster record sales and other industry hurdles to unsatisfying creative choices and interpersonal conflicts, there’s only so much turmoil a group of people can take. Eventually, at least one member might just feel the need to end things and move on.

As the following 10 picks prove, not even the greatest acts are immune from such consequences. Whether due to conventional causes or something more atypical, staying together was simply not in the cards for them (well, at least for a time, as a few eventually reunited).

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